SJM® Pericardial Patch with EnCap™ Technology

IMPROVED HANDLING AND SATURABILITY SUPPORT CARDIOVASCULAR REPAIR

• Ready-to-use, rinseless preparation saves time during procedures
• Bovine pericardium provides improved handling and suturability compared with synthetic patches¹
• The strength of glutaraldehyde-fixed tissue enhances durability and helps resist undesirable changes such as patch shrinkage and aneurysm formation, even in high-stress repairs ^2-6
• Soft, pliable tissue conforms to anatomy and sutures into place with minimal leaking along suture line

ANTI-CALCIFICATION TREATMENT ENHANCES BIOCOMPATIBILITY AND DURABILITY

• Proprietary EnCap AC Technology caps residual aldehydes to reduce antigenicity and cytotoxicity ^5,7,8
• Resists calcification and promotes rapid binds, thorough healing with endothelial cell covering ^7-10
• Improved endothelialization strengthens the reconstruction or repair, helping reduce calcification and other degeneration ^7-9

APPROPRIATE FOR A WIDE RANGE OF CARDIAC AND VASCUALR REPAIRS ⁸

• Annular reconstruction ³
• Endocarditis leaflet repairs
• Septal defect repairs
• Aortic root enlargement
• Pediatric applications ¹¹
• Other vascular repairs

References

1. Crawford, et al. Bovine pericardium for correction of congenital heart defects. Ann Thorac Surg. 1986;41(6):602-5.

2. Frater, et al. Chordal replacement in mitral valve repair. Circulation. 1990;82(5 suppl):IV-125-IV-130.

3. David T, et al. Reconstruction of the mitral annulus - A 10-year experience. J Thorac Cardiovasc Surg. 1995;110(5):1323-32.

4. Bjornstad, et al. Clinical and echocardiographic follow-up after aortic valve reconstruction with bovine or autologous pericardium. Am Heart J. 1996;132(6):1173-8.

5. Gong G, et al. Bioprosthetic cardiac valve degeneration: role of inflammatory and immune reactions. J Heart Valve Dis. 1993;2(6):684-93.

6. Gong G, et al. Aldehyde tanning: the villain in bioprosthetic calcification. Eur J Cardiothorac Surg. 1991;5:288-99.

7. Frater, et al.: Anticalcification, proendothelial, and antiinflammatory effect of postaldehyde polyol treatment of bioprosthetic material. In: Gabbay, et al. ed. Advances in Anticalcific and Antidegenerative Treatment of Heart Valve Bioprostheses. Austin, TX: Silent Partners, Inc.; 1997:105-14.

8. Frater R, et al. Stentless chordally supported mitral bioprosthetic valve. In: Gabbay, et al., eds. New Horizons and the Future of Heart Valve Bioprosthesis. Austin, TX: Silent Partners, Inc.; 1994:103-19.

9. Hoffman D, et al. Spontaneous host endothelial growth on bioprostheses. Circulation. 1992;86[suppl II]:II-75-II-79.

10. Mortz A, et al. Imporved spontaneous endothelialization by postfixation treatment of bovine pericardium. Eur J Cardiothorac Surg. 1991;5:155-9.

11. Hopkins, et at. Surgical Patch Closure of Atrial Septal Defects. Ann Thorac Surg. 2004;77:2144-50.

* There is no clinical data currently available which evaluates the long-term impact of anticalcification tissue treatment in humans.