The proprietary EnCap AC Technology caps residual free aldehydes associated with the glutaraldehyde fixation process to mitigate antigenicity and cytotoxicity and yield a biologically stable patch material. This process has been shown in animals to promote host endothelial covering7 and to minimize the calcification to which regular glutaraldehyde-treated bovine pericardium patches are vulnerable.6
The SJM Pericardial Patch is packaged in sterile water and 2% propylene oxide that, prior to shipment, undergoes a chemical conversion to 2% propylene glycol.
The patch is available in 2x5, 5x10, and 9x14 cm sizes with a thickness of 0.2 to 0.4mm.
References
1Crawford, et al.: Bovine pericardium for correction of congenital heart defects. Ann Thorac Surg 1986;41(6):602-605.
2Frater, et al.: Chordal replacement in mitral valve repair. Circ 1990;82(5 suppl):IV-125-IV-130.
3David T: The surgical treatment of patients with prosthetic valve endocarditis. Sem Thorac & Cardiovasc Surg 1995;7(1):47-53.
4David T: Reconstruction of the mitral annulus - A 10-year experience. J Thorac Cardiovasc Surg 1995;110(5):1323-1332.
5Bjornstad, et al.: Clinical and echocardiographic follow-up after aortic valve reconstruction with bovine or autologous pericardium. Am Heart J 1996;132(6):1173-1178.
6Frater, et al.: Anticalcification, proendothelial, and antiinflammatory effect of postaldehyde polyol treatment of bioprosthetic material. In: Gabbay, et al. ed. Advances in Anticalcific and Antidegenerative Treatment of Heart Valve Bioprostheses. Austin, TX: Silent Partners, Inc.; 1997:105-113.
7Frater R.; Stentless chordally supported mitral bioprosthetic valve. In: Gabbay, et al., eds. New Horizons and the Future of Heart Valve Bioprosthesis. Austin, TX: Silent Partners, Inc.; 1994:103-119.