PressureWire™ Certus FFR Measurement System

Incorporating FFR Measurement into Procedures Significantly Reduces Major Adverse Coronary Events¹

When integrated into lab procedures, measurement of fractional flow reserve (FFR) has been shown to reduce the incidence of adverse events in patients being treated for complex coronary artery disease. Compared to angiography alone, FFR:

• Allows more accurate identification of hemodynamically relevant stenoses, reducing rates of death, myocardial infarction and repeat revascularization²
• Improves outcomes and patient quality of life
• Lowers procedure-related costs
• Does not increase procedure time
• Decreases the amount of contrast agent used

Precise measurement of intravascular pressure relies on the market-leading wire that combines exceptional maneuverability–even in tortuous vessels–and reliable readings to ensure access to accurate information in the cath lab.

Patented Sensor Technology

PressureWire Certus features a proprietary, miniaturized, high-fidelity pressure sensor for measurement of intravascular pressure for accurate FFR measurement. This technology also enables simultaneous measurement of temperature and thermo-dilution low, which can be stored on the RadiAnalyzer Xpress.

Engineered for Exceptional Precision, Control and Reliability

The PressureWire Certus is a reliable, accurate FFR measurement system for complex coronary lesion assessment.

Core Wire

Strengthened core 0.014" wire provides increased torque, making PressureWire Certus less sensitive to prolapse.

Hydrophilic and Hydrophobic Coatings

• Distal polymer sleeve is coated with a hydrophilic outer layer which reduces friction against the vessel wall and increases device compatibility
• A hydrophilic coating enhances overall maneuverability in tortuous vessels by providing better tactile feel and distal access
• The proximal male connector has a hydrophobic coating which increases connector reliability during long procedures

^1,2Tonino PA, De Bruyne B, Pijls NH, et al. Fractional low reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med. 2009;360(3):213-224.

Learn more on our Knowledge Center

Find out more about Physiological Assessment using a guidewire-mounted pressure sensor and its clinical applications in the catheterization laboratory.
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Fractional Flow Reserve (FFR) Measurement for Informed Coronary Disease Intervention

FFR Measurement Correlates to the Likelihood of Ischemia

An FFR measurement above 0.80 indicates normal coronary blood low and a non-significant stenosis. A measurement below 0.75 indicates a high likelihood that a stenosis may be causing ischemia.

Incorporating FFR Measurement into Procedures Significantly Reduces Major Adverse Coronary Events

When integrated into routine lab procedures, measurement of fractional flow reserve (FFR) has been shown to reduce the incidence of adverse events in patients being treated for complex coronary artery disease. Compared to angiography alone, FFR allows physicians to more accurately identify hemodynamically relevant stenoses, reducing rates of death, myocardial infarction and repeat revascularization.¹

Key findings from the FAME study show a 30% reduction in major adverse cardiac event (MACE) rates and significant cost savings without prolonging procedure time.

¹Tonino PA, De Bruyne B, Pijls NH, et al. Fractional low reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med. 2009;360(3):213-224.

Study Reports Integrating FFR into Procedures Improves Outcomes and Reduces Costs

The FAME study, recently published in The New England Journal of Medicine, shows that routine measurement of FFR in patients with complex coronary artery disease reduces MACE and makes stent placement more eficient and more cost-effective.¹

FAME Study Results

Study Methods

• FAME (FFR versus Angiography for Mutilvessel Evaluation)
• Randomized, prospective study – angiography only or angiography plus FFR
• 20 centers in US and Europe
• 1,005 PCI patients undergoing DES stenting for multivessel disease

Outcomes

Compared to angiography-only procedures, FAME shows that FFR:

• Reduces composite rates of death, myocardial infarction, re-PCI, and CABG at one year by 28%
• Reduces mortality and myocardial infarction at one year by 34%
• Is cost-saving and does not prolong procedure time
• Decreases amount of contrast agent used
• Results in similar, if not better, functional status

¹Tonino PA, De Bruyne B, Pijls NH, et al. Fractional low reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med. 2009;360(3):213-224.

Read more about the FAME study at www.famestudy.com